Released on: October 27, 2008, 7:22 am

Press Release Author: Definiens

Industry: Biotech

Press Release Summary: Automated Image Analysis Technology Supports the Development
of Disease-Specific Biomarker Models and Companion Diagnostics

Press Release Body: Munich / Morristown, NJ - October 27, 2008 - Definiens, the
number one Enterprise Image Intelligence(tm) company, is unveiling the latest version
of its image analysis application Definiens TissueMap 3.0. The application
quantitatively assesses cellular structures and substructures in whole tissue
sections and tissue microarrays, helping researchers discover, validate and measure
new drug targets and disease-specific biomarkers.

The discovery of biomarker models and the increasing use of imaging technologies to
acquire accurate measurements of disease parameters are significantly impacting the
drug development process. However, the detailed quantification of key parameters,
which is largely performed manually, remains a time-consuming and often inconsistent
process.

Definiens TissueMap 3.0 accelerates image analysis by automatically identifying and
quantifying nuclear, cytoplasmic and membrane markers in epithelial tumors and
xenografts, providing researchers with fast, accurate and reproducible results. The
application can handle both whole section slides and tissue microarrays and can
differentiate between viable and necrotic tissue in xenografts. Implementing
automated image analysis enables biotechnology and pharmaceutical companies to
improve the prioritization of quality drug candidates by identifying poor candidates
earlier in the drug development process and thereby realize substantial cost
savings.

"Intelligent image analysis technology is vital to the development of predictive
biomarker models and the advancement of translational research," said Manfred
Voglmaier, Vice President Business Development Life Sciences at Definiens.
"Definiens TissueMap 3.0 supports researchers in extracting critical information
from images throughout the drug discovery and development process."

Definiens TissueMap 3.0 comes with a set of pre-defined tools to detect and quantify
specific morphological or functional structures in tissues, such as tumor sections.
The application is built on Definiens XD, Definiens' multidimensional image analysis
platform, which is highly flexible, scalable and supports a wide range of image
acquisition devices.

Definiens TissueMap 3.0 will be introduced at Pathology Visions 2008 and will be
commercially available worldwide starting November 2008.

Definiens in Life Sciences
Definiens supports Life Science organizations by automating image analysis on an
enterprise level, from drug discovery to diagnostics. Its image analysis software
enables pharmaceutical and biomedical companies to interpret vast numbers of digital
images accurately and consistently. Definiens applications improve the measurement
of cell assays, the examination of tissue samples and the interpretation of
non-invasive imaging, helping organizations to advance translational research and
personalized medicine.

About Definiens
Definiens is the number one Enterprise Image Intelligence company for analyzing and
interpreting images on every scale, from microscopic cell structures to satellite
images. The Definiens Cognition Network Technology(r), developed by Nobel Laureate
Prof. Gerd Binnig and his team, is an advanced and robust context-based technology
designed to fulfill the image analysis requirements of the Medical, Life Science,
and Earth Science markets. The technology is modeled on the powerful human cognitive
perception processes to extract intelligence from images. Definiens provides
organizations with faster image analysis results, allowing deeper insights enabling
better business decisions. The company is headquartered in Munich, Germany and has
offices in the United States. Further information is available at www.definiens.com.

Definiens, Definiens Cellenger, Definiens Cognition Network Technology, Definiens
eCognition, Enterprise Image Intelligence and Understanding Images are trademarks or
registered trademarks of Definiens.


Web Site: http://www.definiens.com/news-room_138_42_0.html

Contact Details: Garry Clark
Ricochet PR
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NY, NY 10006

212-379-3300
GClark@Ricochetpr.com